Tuesday, October 27, 2009

HIV Attacks Body's Immune System

By Mark John Getto
HIV stands for human immunodeficiency virus. It breaks down the immune system -our body's protection against disease. HIV destroys white blood cells that are required to fight infection. As the white cell count falls to dangerous levels infections and diseases emerge.

HIV is the virus that causes AIDS (acquired immunodeficiency syndrome), a life-threatening disease. Normally, the immune system produces white blood cells and antibodies that attack viruses and bacteria. HIV thus makes its victims easily vulnerable to any infection. Gastrointestinal symptoms include poor appetite, diarrhoea, severe fatigue that results in rapid weight loss etc. The virus attacks your CD4 cells (or T4 cells), which are necessary to fight off illnesses.

HIV has been given this name because its long-term effect is to attack the immune system of the body, making it weak and deficient. We live virtually in a sea of microorganisms and at every moment an enormous number of them are entering our body. HIV-1 is predominant worldwide. Whenever people refer to HIV, it is understood to be HIV-1. HIV-infected men, for instance, are eight times more likely than HIV-infected women to develop a skin cancer known as Kaposi's sarcoma.

HIV fusion inhibitors work by blocking HIV's ability to infect healthy CD4+ cells. Integrase inhibitors work by blocking integrase, the enzyme that HIV uses to integrate genetic material of the virus into its target host cell. HIV-infected children frequently are slow to reach important milestones in motor skills and mental development such as crawling, walking and speaking. As the disease progresses, many children develop neurologic problems such as difficulty walking, poor school performance, seizures, and other symptoms of HIV encephalopathy. HIV/AIDS is always fatal and it's necessary to understand how it works as much as possible to prevent one from getting the disease.

HIV can cross the placenta during pregnancy, infect the baby during the birth and, unlike most STDs, can also infect the baby through breastfeeding. HIV is carried in blood, sperm, seminal fluid, vaginal fluid (including menstrual fluid) and breast milk. It can't pass through unbroken skin, however, and it isn't airborne like flu or the common cold - it has to enter the body via the bloodstream or through sex. HIV is much more easily spread in the presence of inflammatory STDs such as gonorrhea.

Infection at delivery is the most common mode of transmission. A number of factors influence the risk of infection, particularly the viral load of the mother at birth - the higher the load, the higher the risk. Infections that a healthy person can fight off have the ability to take hold in someone suffering from AIDS. An HIV/AIDS patient can display any number of symptoms, with those symptoms depending on which stage of the disease the person is experiencing. Infection with HIV occurs by the transfer of blood , semen , vaginal fluid , pre-ejaculate , or breast milk . Within these bodily fluids , HIV is present as both free virus particles and virus within infected immune cells .

Opportunistic infections are common in people with AIDS. Nearly every organ system is affected.

Related: transmitted, testing, test, syphilis, std, sexually, hiv, gonorrhea, disease, confidential, new york, anonymous, aids

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